Encyclopedia entry · Longevity
DSIP
Delta Sleep-Inducing Peptide
DSIP (Delta Sleep-Inducing Peptide) is a nine-amino-acid peptide first isolated by Schoenenberger and Monnier in 1977 from the cerebral venous blood of rabbits undergoing electrical stimulation that induced delta-wave sleep. Subsequent decades of research have explored a wide range of effects beyond sleep, including stress-response modulation, opioid-withdrawal effects, and neuroendocrine signalling. The biological function remains incompletely characterised. UK availability is research-tier.
What the molecule is
- · Nine-amino-acid peptide originally isolated from rabbit cerebral venous blood.
- · First named for its association with delta-wave EEG sleep activity.
- · Endogenous in human plasma, with circadian variation reported.
- · Mechanism of action remains incompletely characterised despite decades of research.
What the literature shows
- · Original 1977 isolation by Schoenenberger and Monnier.
- · Animal-model evidence for sleep effects (mixed and species-dependent).
- · Stress-response and HPA-axis modulation in published preclinical work.
- · Opioid-withdrawal mitigation in older clinical case reports.
UK regulatory status
- · Not a controlled drug under the Misuse of Drugs Act 1971.
- · Not scheduled under the Psychoactive Substances Act 2016.
- · No UK marketing authorisation as a medicine.
- · Research-use-only framing required for UK sale.
Where UK researchers source DSIP
See CoA Trust Index →Ranked by CoA Trust tier (strong, partial, weak). Editorial commentary on retailers that list DSIP or compounds in the same category. We earn a referral fee when readers click through and convert.
Researchers wanting named-stack bundles (Wolverine, KLOW, Glow) and CoAs that can be QR-verified to a named third-party lab.
Research peptide retailer · Wolverine Stack £29.99, BPC-157 single from £14.99
Nottingham-based research peptide retailer (Bio Research Ltd, since 2024). Bundles and stacks are the hero SKU (Wolverine BPC-157 + TB-500, Tesamorelin + Ipamorelin 3:1, KLOW, Glow). Janoshik third-party CoAs published per batch with QR-code verification. 10-vial bulk packs alongside singles. Wholesale tier above 11 vials.
Best for per-batch CoA library
Research peptide retailer · BPC-157 5mg £13.99, TB-500 5mg £36
Long-established UK research peptide supplier. 12 years trading, 15,000+ customers. Operates a public CoA subdomain (coa.purepeptidesuk.com) with downloadable per-batch certificates linked from every PDP. Dual-tier purity (Standard vs Premium with endotoxin LAL + heavy-metal testing on Premium).
Researchers who want transparent third-party HPLC batch documents and a less hyped brand voice.
Research peptide retailer · Per peptide, varies
UK research peptide retailer with third-party HPLC plus transparent batch documentation. Plays the credibility lane alongside Pure Peptides UK and Tide Labs.
Researchers who weight UKAS lab accreditation specifically and want the loudest external-verification claim in the segment.
Research peptide retailer · Per peptide, varies
UK research peptide retailer leaning on UKAS-verified HPLC as the sole-in-UK trust claim. Narrower catalogue than UKPeptides or Pure Peptides UK but the lab-verification angle is the loudest in the segment.
Best for classic peptides catalogue
Research peptide retailer · Per peptide, varies
Long-trading UK research peptide retailer (2012). Heavy on classic compounds (BPC-157, TB-500, GHK-Cu, CJC-1295, Ipamorelin, MOTS-c). No GLP-1, no cosmetic line. CoA gated via on-site contact form (request lab report per product). On-site CusRev reviews 5.0 average, not Trustpilot. Reconstitution calculator on-site.
Buyers who want personal owner-accountability via WhatsApp and prefer CoAs visible in product images rather than gated. Strong stack catalogue.
Research peptide retailer · BPC-157 from £18.99, Wolverine Stack discounted
Family-run Newcastle research peptide retailer (Rian, Victoria, Leah Redman). Owner-fronted WhatsApp on every page. CoAs photographed into the product gallery (COA in image) rather than gated. Heavy on named-stack bundles (Wolverine, Hulk, Ultimate Bundle). Crisp live chat sitewide. Personal accountability is the trust play.
Where to learn more
- · PubMed search: "Delta Sleep-Inducing Peptide" and "DSIP stress".
- · Schoenenberger and Monnier 1977 original isolation paper.
- · Our function hub: Longevity peptides.
PeptideClear does not sell, dispense, prescribe, or recommend DSIP for any specific person. This page is editorial commentary on the published preclinical and clinical research literature and the UK retail landscape.
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Buy DSIP in the UK
UK retailers compared by price, Trust Index, and CoA practice. Editorial commentary only. Research use only.