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Named peptide stack · Longevity

Sleep Stack

The Sleep Stack is a smaller research-peptide pairing focused on delta-wave sleep and pineal-axis regulation. Typical composition: DSIP (Delta Sleep-Inducing Peptide) and Epitalon. Both are research-tier. The literature is preclinical and the function of DSIP remains incompletely characterised after four decades of research.

DSIP Epitalon

Why researchers pair these compounds

DSIP was first isolated in 1977 from rabbit cerebral venous blood during electrically-induced delta-wave sleep. The name reflects the discovery context. The actual biological role of DSIP across species and contexts remains contested in the literature.

Epitalon contributes pineal-melatonin-axis signal from the Russian research lineage. Combining the two targets two distinct sleep-regulation pathways.

Both compounds are smaller-volume in the UK research peptide market. CoA documentation availability is more variable than for BPC-157 or GH-secretagogues.

Mechanism

DSIP modulation of HPA-axis and opioid-system signalling in animal models. Epitalon regulation of pineal melatonin output and circadian clock genes in Russian preclinical work.

Components

DSIP

Nine-amino-acid peptide first isolated 1977. Sleep, stress-response and opioid-withdrawal research interest.

Encyclopedia entry

Epitalon

Russian-research tetrapeptide. Pineal-melatonin-axis literature.

Encyclopedia entry

Who this is for

UK retailers stocking the components

See CoA Trust Index →

Ranked by CoA Trust tier. Editorial commentary based on publicly available information. We earn a referral fee when readers click through and convert.

Researchers wanting named-stack bundles (Wolverine, KLOW, Glow) and CoAs that can be QR-verified to a named third-party lab.

XL PeptidesCoA: strong

Research peptide retailer · Wolverine Stack £29.99, BPC-157 single from £14.99

Nottingham-based research peptide retailer (Bio Research Ltd, since 2024). Bundles and stacks are the hero SKU (Wolverine BPC-157 + TB-500, Tesamorelin + Ipamorelin 3:1, KLOW, Glow). Janoshik third-party CoAs published per batch with QR-code verification. 10-vial bulk packs alongside singles. Wholesale tier above 11 vials.

Best for per-batch CoA library

Pure Peptides UKCoA: strong

Research peptide retailer · BPC-157 5mg £13.99, TB-500 5mg £36

Long-established UK research peptide supplier. 12 years trading, 15,000+ customers. Operates a public CoA subdomain (coa.purepeptidesuk.com) with downloadable per-batch certificates linked from every PDP. Dual-tier purity (Standard vs Premium with endotoxin LAL + heavy-metal testing on Premium).

Researchers who want transparent third-party HPLC batch documents and a less hyped brand voice.

Research peptide retailer · Per peptide, varies

UK research peptide retailer with third-party HPLC plus transparent batch documentation. Plays the credibility lane alongside Pure Peptides UK and Tide Labs.

Researchers who weight UKAS lab accreditation specifically and want the loudest external-verification claim in the segment.

Tide LabsCoA: partial

Research peptide retailer · Per peptide, varies

UK research peptide retailer leaning on UKAS-verified HPLC as the sole-in-UK trust claim. Narrower catalogue than UKPeptides or Pure Peptides UK but the lab-verification angle is the loudest in the segment.

Best for classic peptides catalogue

Peptides UKCoA: partial

Research peptide retailer · Per peptide, varies

Long-trading UK research peptide retailer (2012). Heavy on classic compounds (BPC-157, TB-500, GHK-Cu, CJC-1295, Ipamorelin, MOTS-c). No GLP-1, no cosmetic line. CoA gated via on-site contact form (request lab report per product). On-site CusRev reviews 5.0 average, not Trustpilot. Reconstitution calculator on-site.

Buyers who want personal owner-accountability via WhatsApp and prefer CoAs visible in product images rather than gated. Strong stack catalogue.

Dr PeptidesCoA: partial

Research peptide retailer · BPC-157 from £18.99, Wolverine Stack discounted

Family-run Newcastle research peptide retailer (Rian, Victoria, Leah Redman). Owner-fronted WhatsApp on every page. CoAs photographed into the product gallery (COA in image) rather than gated. Heavy on named-stack bundles (Wolverine, Hulk, Ultimate Bundle). Crisp live chat sitewide. Personal accountability is the trust play.

Frequently asked questions

Does DSIP actually induce sleep?

The preclinical literature is mixed and species-dependent. The name reflects the discovery context, not a settled functional claim.

Is the Sleep Stack UK-licensed?

No. Both compounds are research-tier. They are not UK clinical medicines for sleep disorders.

PeptideClear does not sell, dispense, prescribe, or recommend Sleep Stack for any specific person. This page is editorial commentary on the published preclinical literature and the UK retail landscape. Every research peptide on this page is sold under research-use-only framing.

Read our full methodology and how we are funded.

Reviewed by Oliver Mackman, editorial director · last reviewed 2026-05-20