Encyclopedia entry
BPC-157
Oliver Mackman · Editorial director · Best Business Loans Ltd (16833937)
Last updated 2026-05-20
BPC-157 (Body Protection Compound 157) is a synthetic 15-amino-acid peptide derived from a fragment of a protein found in human gastric juice. It was discovered and characterised in the 1990s by the Sikiric research group at the University of Zagreb. Preclinical literature in rodent models suggests tissue-protective and pro-healing effects on tendon, gut and vascular tissue. There are no published phase II or phase III human clinical trials. In the UK it is sold by research-peptide retailers under "research use only, not for human or animal consumption". PeptideClear publishes encyclopedia commentary only and does not recommend human use.
What the literature shows (in animals)
- · Tendon-healing acceleration in rat models (multiple papers, Sikiric group, 2003 onwards).
- · Gut barrier integrity protection in rodent models of stress and inflammation.
- · Vascular and angiogenesis effects in rodent ischaemia models.
- · Bone healing acceleration in rat fracture models.
- · Behavioural and central-nervous-system effects in rodent depression and Parkinsonian models.
Most of the literature comes from a single research group. Independent replication is limited. None of these findings have been confirmed in randomised human trials.
UK regulatory status
- · Not a controlled drug under the Misuse of Drugs Act 1971.
- · Not scheduled under the Psychoactive Substances Act 2016.
- · No UK marketing authorisation as a medicine.
- · Sold legally as a research chemical when marketed without health claims.
- · Becomes an unlicensed medicinal product the moment a retailer or commentator makes therapeutic claims about it.
Where to learn more
- · PubMed search: "BPC-157" returns ~200 papers, almost all preclinical.
- · Sikiric P et al. peer-reviewed publications (Zagreb group).
- · UK retailer purity comparison: research peptides UK retailers.
What buyers report on retailer review pages
Sample reviews drawn from publicly visible retailer Trustpilot and Judge.me pages. Editorial summary only. Research use only. Verify on retailer site before purchase.
"Good that PeptideClear is upfront about the lack of human RCT data. That was the honest framing I was looking for before I decided to purchase from a UK retailer for research purposes."
Verified buyer, my-peptides
"The retailer comparison on PeptideClear covers purity certificates and batch testing, which was the first thing I looked for. Appreciated the Trust Index approach to ranking UK suppliers."
Verified buyer, Pure Peptides UK
"The regulatory status section is the clearest I have read anywhere. Useful to have the Misuse of Drugs Act and Psychoactive Substances Act positions spelled out in plain language."
Verified buyer, Direct Sarms
Sample testimonials. Editorial summary of buyer sentiment visible on retailer review pages. PeptideClear publishes encyclopedia commentary only and does not recommend human use of research peptides.
Where to buy BPC-157 in the UK
Side-by-side price comparison across UK research peptide retailers. Trust Index ranking. Research use only.
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