Methodology

PeptideClear publishes editorial comparison across four UK peptide categories: cosmetic skincare peptides, ingestible collagen, research peptides, and prescription GLP-1 weight loss. Each category has its own methodology page because the regulatory regimes differ (cosmetic, food supplement, research-use-only chemical, and POM medicine respectively). The shared framework below covers source-tier ranking, comparison criteria, refresh cadence (quarterly, with monthly Trustpilot pulls), and a documented conflict-of-interest position. Editorial byline: Oliver Mackman. We are not a pharmacy and not a clinic.

Methodology by category

· GLP-1 clinics and online pharmacies, licensed prescription medicines (semaglutide, tirzepatide). GPhC + GMC + trading-history criteria.
· Research peptides, research-use-only chemicals. CoA Trust Index criteria. Linked to the CoA Trust Index.
· Cosmetic peptide skincare, licensed topicals. INCI position, formulation transparency, clinical-claim substantiation.
· Collagen supplements, food-supplement category. Source, dose, peer-reviewed substantiation.
· Longevity clinics, emerging UK private-clinic tier.

The detail below is the shared framework that all five category methodologies apply.

Criteria for clinic and pharmacy listings

· UK-licensed pharmacy (GPhC registration verified)
· Prescriber on payroll or under contract (named, not anonymous)
· Published, transparent pricing
· Published switching, pause, and cancellation terms
· At least 12 months of UK trading history
· Public Trustpilot or similar review record
· No grey-market or compounded GLP-1 supply
· Cold-chain delivery infrastructure for tirzepatide and semaglutide

Comparison criteria (per clinic / pharmacy profile)

· Onboarding (questionnaire vs full clinical consultation)
· Coach, app, and check-in cadence
· Cost per typical month at a typical maintenance dose
· Switching policy (Wegovy to Mounjaro and vice versa)
· Pause and cancellation terms
· Maintenance-dose policy at goal weight
· HRT or fertility-aware co-prescribing (where relevant)
· UK delivery coverage
· Trustpilot rating and review volume

Refresh cadence

Clinic and pharmacy profiles are refreshed quarterly or whenever a partner notifies us of a material change (price, policy, registration). Trustpilot pulls are refreshed monthly via API.

Conflict of interest

Some clinics and pharmacies on the site are referral partners. Inclusion in the directory is not contingent on a referral relationship. Our editorial framework is documented in our editorial policy; our funding model in how we are funded.