Encyclopedia entry · GH Secretagogues
CJC-1295
CJC-1295 (with and without DAC modification)
CJC-1295 is a 30-amino-acid synthetic analogue of GHRH (Growth-Hormone-Releasing Hormone). It is sold in two forms: with DAC (Drug Affinity Complex, a maleimidopropionic acid modification that binds the peptide to serum albumin) and without DAC. With DAC, half-life extends from minutes to roughly 6 to 8 days. Without DAC, action is short-lived.
What the molecule is
- · 30-residue GHRH analogue developed for sustained GH release.
- · DAC variant adds a maleimidopropionic acid linker that covalently binds the peptide to serum albumin in vivo.
- · Acts on the pituitary GHRH receptor to stimulate endogenous GH release.
- · Frequently paired with ghrelin mimetics (Ipamorelin, GHRP-2) in research stacking because the two receptors act on different pathways.
What the literature shows
- · Preclinical and early human safety work published by ConjuChem Inc. in the 2000s.
- · Animal-model evidence for sustained increases in GH and IGF-1 with DAC variant.
- · Pulsatile GH-release pattern preserved with non-DAC variant; sustained elevation observed with DAC.
- · No phase III approved indication. Research-tier in all Western jurisdictions.
UK regulatory status
- · Not a controlled drug under the Misuse of Drugs Act 1971.
- · Not scheduled under the Psychoactive Substances Act 2016.
- · No UK marketing authorisation as a medicine.
- · Sold legally as a research chemical under research-use-only framing.
Where UK researchers source CJC-1295
See CoA Trust Index →Ranked by CoA Trust tier (strong, partial, weak). Editorial commentary on retailers that list CJC-1295 or compounds in the same category. We earn a referral fee when readers click through and convert.
Researchers wanting named-stack bundles (Wolverine, KLOW, Glow) and CoAs that can be QR-verified to a named third-party lab.
Research peptide retailer · Wolverine Stack £29.99, BPC-157 single from £14.99
Nottingham-based research peptide retailer (Bio Research Ltd, since 2024). Bundles and stacks are the hero SKU (Wolverine BPC-157 + TB-500, Tesamorelin + Ipamorelin 3:1, KLOW, Glow). Janoshik third-party CoAs published per batch with QR-code verification. 10-vial bulk packs alongside singles. Wholesale tier above 11 vials.
Best for per-batch CoA library
Research peptide retailer · BPC-157 5mg £13.99, TB-500 5mg £36
Long-established UK research peptide supplier. 12 years trading, 15,000+ customers. Operates a public CoA subdomain (coa.purepeptidesuk.com) with downloadable per-batch certificates linked from every PDP. Dual-tier purity (Standard vs Premium with endotoxin LAL + heavy-metal testing on Premium).
Researchers who want transparent third-party HPLC batch documents and a less hyped brand voice.
Research peptide retailer · Per peptide, varies
UK research peptide retailer with third-party HPLC plus transparent batch documentation. Plays the credibility lane alongside Pure Peptides UK and Tide Labs.
Researchers who weight UKAS lab accreditation specifically and want the loudest external-verification claim in the segment.
Research peptide retailer · Per peptide, varies
UK research peptide retailer leaning on UKAS-verified HPLC as the sole-in-UK trust claim. Narrower catalogue than UKPeptides or Pure Peptides UK but the lab-verification angle is the loudest in the segment.
Best for classic peptides catalogue
Research peptide retailer · Per peptide, varies
Long-trading UK research peptide retailer (2012). Heavy on classic compounds (BPC-157, TB-500, GHK-Cu, CJC-1295, Ipamorelin, MOTS-c). No GLP-1, no cosmetic line. CoA gated via on-site contact form (request lab report per product). On-site CusRev reviews 5.0 average, not Trustpilot. Reconstitution calculator on-site.
Buyers who want personal owner-accountability via WhatsApp and prefer CoAs visible in product images rather than gated. Strong stack catalogue.
Research peptide retailer · BPC-157 from £18.99, Wolverine Stack discounted
Family-run Newcastle research peptide retailer (Rian, Victoria, Leah Redman). Owner-fronted WhatsApp on every page. CoAs photographed into the product gallery (COA in image) rather than gated. Heavy on named-stack bundles (Wolverine, Hulk, Ultimate Bundle). Crisp live chat sitewide. Personal accountability is the trust play.
Where to learn more
- · PubMed search: "CJC-1295" and "tesamorelin GHRH analogue".
- · Teichman SL et al. (Journal of Clinical Endocrinology and Metabolism) early human work.
- · Our function hub: GH Secretagogues.
- · CoA Trust Index for UK retailer documentation.
PeptideClear does not sell, dispense, prescribe, or recommend CJC-1295 for any specific person. This page is editorial commentary on the published preclinical and clinical research literature and the UK retail landscape.
Read our full methodology and how we are funded.
Ready to buy
Buy CJC-1295 in the UK
UK retailers compared by price, Trust Index, and CoA practice. Editorial commentary only. Research use only.