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Regulatory tracker

MHRA enforcement and safety tracker

Oliver Mackman · Editorial director · Best Business Loans Ltd (16833937)

Last updated 2026-07-13

The MHRA published 24 items in the 90 days to 2026-07-13, of which 3 relate to weight-loss medicines or peptides, 3 concern enforcement against illegal or unlicensed supply, and 4 are formal Drug Safety Updates. This page restates what the regulator published and links to each gov.uk original. It is a reporting record, not advice. If a medicine you take appears in a Drug Safety Update, the item itself tells you what the MHRA asks patients and prescribers to do, and your prescriber or pharmacist is the person to speak to.

24

MHRA items in the window

3

Relevant to this site

3

Enforcement actions

4

Drug Safety Updates

What the MHRA said about weight-loss medicines and peptides

The subset that touches the categories this site covers. Everything else the regulator published in the same window is in the full table below.

Announcement 2026-07-03

Semaglutide (Wegovy) approved to treat form of liver disease

The semaglutide injection has been approved to treat metabolic-associated steatohepatitis (MASH) in adults with moderate-to-advanced liver fibrosis.

Read the MHRA original on gov.uk
Enforcement 2026-06-18

Warning on promoting newly licensed prescription-only medicines and unlicensed medicines for weight management

The MHRA, Advertising Standards Authority, and the General Pharmaceutical Council have issued a warning to businesses seeking to promote newly authorised medicines, as well as those that do not yet have a marketing authorisa.

Read the MHRA original on gov.uk
Announcement 2026-06-11

First GLP-1 tablet for weight loss approved in the UK

Having met the MHRA’s rigorous standards of safety, quality and effectiveness, the semaglutide tablet has been approved in the UK for weight loss and weight management.

Read the MHRA original on gov.uk

Full MHRA record, last 90 days

Everything the MHRA published between 2026-04-30 and 2026-07-10, newest first. We list the full record rather than only the convenient parts, so the selection above can be checked against what was actually published.

Date Type Item Relevant here
2026-07-10 Announcement Yellow Cards: bad in football; brilliant in patient safety No
2026-07-09 Announcement MHRA safety review gives UK plasma donations go ahead No
2026-07-09 Announcement Heat, travel and late nights: How summer can affect your medicines and how to stay safe No
2026-07-08 Announcement Nerandomilast (Jascayd) approved to treat adult patients with Idiopathic Pulmonary Fibrosis and Progressive Pulmonary Fibrosis No
2026-07-08 Enforcement Four sentenced to nearly 15 years combined jail time following major MHRA investigation into illegal online supply of medicines No
2026-07-06 Announcement MHRA approves Retifanlimab (ZYNYZ) for the treatment of advanced Merkel cell skin cancer No
2026-07-03 Announcement Semaglutide (Wegovy) approved to treat form of liver disease Yes
2026-07-02 Announcement Making regulation a catalyst, not a barrier, for UK life sciences No
2026-07-01 Enforcement MHRA secures convictions after a decade-long investigation into falsely marked baby-feeding devices No
2026-07-01 Announcement MHRA authorises gemcitabine delivery system for adults with BCG-unresponsive high-risk non-muscle invasive bladder cancer No
2026-06-19 Announcement Update on the PATHWAYS clinical trial No
2026-06-18 Enforcement Warning on promoting newly licensed prescription-only medicines and unlicensed medicines for weight management Yes
2026-06-16 Drug safety update ACE-inhibitors: Be aware of the distinction between bradykinin- and histamine-mediated angioedema, as treatment strategies differ significantly No
2026-06-15 Announcement Unique liaison programme set to reinforce close collaboration between MHRA and FDA No
2026-06-12 Announcement Lower dose needle-free allergy treatment approved for younger children No
2026-06-12 Announcement MHRA scientific leader recognised in 2026 King’s Birthday Honours No
2026-06-11 Announcement MHRA landmark report reveals public views on AI in healthcare No
2026-06-11 Announcement First GLP-1 tablet for weight loss approved in the UK Yes
2026-06-10 Announcement Pioneering AI health innovations regulatory sandbox launched No
2026-06-09 Announcement Nipocalimab (Imaavy) authorised to treat adults and adolescents with generalised myasthenia gravis No
2026-06-09 Announcement MHRA launches AI sandbox to accelerate medicines development and improve safety No
2026-05-20 Drug safety update Amiodarone: reminder of risks of treatment and need for patient monitoring and supervision No
2026-05-11 Drug safety update Finasteride and Dutasteride – updated safety warnings for psychiatric side effects and sexual dysfunction No
2026-04-30 Drug safety update Nasal decongestant sprays and drops containing xylometazoline hydrochloride / oxymetazoline hydrochloride: increased risk of rebound congestion, rhinitis medicamentosa, and tachyphylaxis with overuse No
MHRA items published in the 90 days to 2026-07-13, by date and type
DateTypeItemRelevant to weight-loss medicines or peptides
2026-07-10AnnouncementYellow Cards: bad in football; brilliant in patient safetyNo
2026-07-09AnnouncementMHRA safety review gives UK plasma donations go aheadNo
2026-07-09AnnouncementHeat, travel and late nights: How summer can affect your medicines and how to stay safeNo
2026-07-08AnnouncementNerandomilast (Jascayd) approved to treat adult patients with Idiopathic Pulmonary Fibrosis and Progressive Pulmonary FibrosisNo
2026-07-08EnforcementFour sentenced to nearly 15 years combined jail time following major MHRA investigation into illegal online supply of medicinesNo
2026-07-06AnnouncementMHRA approves Retifanlimab (ZYNYZ) for the treatment of advanced Merkel cell skin cancerNo
2026-07-03AnnouncementSemaglutide (Wegovy) approved to treat form of liver diseaseYes
2026-07-02AnnouncementMaking regulation a catalyst, not a barrier, for UK life sciencesNo
2026-07-01EnforcementMHRA secures convictions after a decade-long investigation into falsely marked baby-feeding devicesNo
2026-07-01AnnouncementMHRA authorises gemcitabine delivery system for adults with BCG-unresponsive high-risk non-muscle invasive bladder cancerNo
2026-06-19AnnouncementUpdate on the PATHWAYS clinical trialNo
2026-06-18EnforcementWarning on promoting newly licensed prescription-only medicines and unlicensed medicines for weight managementYes
2026-06-16Drug safety updateACE-inhibitors: Be aware of the distinction between bradykinin- and histamine-mediated angioedema, as treatment strategies differ significantlyNo
2026-06-15AnnouncementUnique liaison programme set to reinforce close collaboration between MHRA and FDANo
2026-06-12AnnouncementLower dose needle-free allergy treatment approved for younger childrenNo
2026-06-12AnnouncementMHRA scientific leader recognised in 2026 King’s Birthday HonoursNo
2026-06-11AnnouncementMHRA landmark report reveals public views on AI in healthcareNo
2026-06-11AnnouncementFirst GLP-1 tablet for weight loss approved in the UKYes
2026-06-10AnnouncementPioneering AI health innovations regulatory sandbox launchedNo
2026-06-09AnnouncementNipocalimab (Imaavy) authorised to treat adults and adolescents with generalised myasthenia gravisNo
2026-06-09AnnouncementMHRA launches AI sandbox to accelerate medicines development and improve safetyNo
2026-05-20Drug safety updateAmiodarone: reminder of risks of treatment and need for patient monitoring and supervisionNo
2026-05-11Drug safety updateFinasteride and Dutasteride – updated safety warnings for psychiatric side effects and sexual dysfunctionNo
2026-04-30Drug safety updateNasal decongestant sprays and drops containing xylometazoline hydrochloride / oxymetazoline hydrochloride: increased risk of rebound congestion, rhinitis medicamentosa, and tachyphylaxis with overuseNo

Source: gov.uk MHRA announcements feed and MHRA Drug Safety Update feed

View as plain-text Markdown
### MHRA items published in the 90 days to 2026-07-13, by date and type

| Date | Type | Item | Relevant to weight-loss medicines or peptides |
| --- | --- | --- | --- |
| 2026-07-10 | Announcement | Yellow Cards: bad in football; brilliant in patient safety | No |
| 2026-07-09 | Announcement | MHRA safety review gives UK plasma donations go ahead | No |
| 2026-07-09 | Announcement | Heat, travel and late nights: How summer can affect your medicines and how to stay safe | No |
| 2026-07-08 | Announcement | Nerandomilast (Jascayd) approved to treat adult patients with Idiopathic Pulmonary Fibrosis and Progressive Pulmonary Fibrosis | No |
| 2026-07-08 | Enforcement | Four sentenced to nearly 15 years combined jail time following major MHRA investigation into illegal online supply of medicines | No |
| 2026-07-06 | Announcement | MHRA approves Retifanlimab (ZYNYZ) for the treatment of advanced Merkel cell skin cancer | No |
| 2026-07-03 | Announcement | Semaglutide (Wegovy) approved to treat form of liver disease | Yes |
| 2026-07-02 | Announcement | Making regulation a catalyst, not a barrier, for UK life sciences | No |
| 2026-07-01 | Enforcement | MHRA secures convictions after a decade-long investigation into falsely marked baby-feeding devices | No |
| 2026-07-01 | Announcement | MHRA authorises gemcitabine delivery system for adults with BCG-unresponsive high-risk non-muscle invasive bladder cancer | No |
| 2026-06-19 | Announcement | Update on the PATHWAYS clinical trial | No |
| 2026-06-18 | Enforcement | Warning on promoting newly licensed prescription-only medicines and unlicensed medicines for weight management | Yes |
| 2026-06-16 | Drug safety update | ACE-inhibitors: Be aware of the distinction between bradykinin- and histamine-mediated angioedema, as treatment strategies differ significantly | No |
| 2026-06-15 | Announcement | Unique liaison programme set to reinforce close collaboration between MHRA and FDA | No |
| 2026-06-12 | Announcement | Lower dose needle-free allergy treatment approved for younger children | No |
| 2026-06-12 | Announcement | MHRA scientific leader recognised in 2026 King’s Birthday Honours | No |
| 2026-06-11 | Announcement | MHRA landmark report reveals public views on AI in healthcare | No |
| 2026-06-11 | Announcement | First GLP-1 tablet for weight loss approved in the UK | Yes |
| 2026-06-10 | Announcement | Pioneering AI health innovations regulatory sandbox launched | No |
| 2026-06-09 | Announcement | Nipocalimab (Imaavy) authorised to treat adults and adolescents with generalised myasthenia gravis | No |
| 2026-06-09 | Announcement | MHRA launches AI sandbox to accelerate medicines development and improve safety | No |
| 2026-05-20 | Drug safety update | Amiodarone: reminder of risks of treatment and need for patient monitoring and supervision | No |
| 2026-05-11 | Drug safety update | Finasteride and Dutasteride – updated safety warnings for psychiatric side effects and sexual dysfunction | No |
| 2026-04-30 | Drug safety update | Nasal decongestant sprays and drops containing xylometazoline hydrochloride / oxymetazoline hydrochloride: increased risk of rebound congestion, rhinitis medicamentosa, and tachyphylaxis with overuse | No |

Source: gov.uk MHRA announcements feed and MHRA Drug Safety Update feed
How to read this tracker
“A rolling window is honest but it is not history. Items drop off this page after ninety days, so an absence here means the MHRA has not published on it recently, not that nothing has ever been published. Read the enforcement rows as evidence that illegal supply is actively prosecuted in the UK, and read a quiet period as ordinary rather than as reassurance about any particular seller.”
OM

Oliver Mackman

Director, PeptideClear UK

Reviewed 13 July 2026

Methodology

  • Source: the gov.uk MHRA news and communications feed plus the MHRA Drug Safety Update feed, fetched on a schedule by a script in this repository. No item is written by hand.
  • Window: a rolling 90 days. Older items leave the table when they fall outside it.
  • Type: an item is a Drug Safety Update if it came from that feed. Otherwise it is classified as Enforcement when its title or summary refers to prosecution, sentencing, illegal or unlicensed supply, falsified or counterfeit product, seizure, or a formal warning. Everything else is an Announcement.
  • Relevance: an item is flagged relevant when the fetch matched it to a compound we track, or when its title or summary names a GLP-1 medicine, a weight-loss or obesity medicine, or a peptide.
  • Classification is by keyword and is deliberately generous. Read the linked gov.uk original before relying on any row, and treat our label as a signpost rather than a legal characterisation.

Last fetched 2026-07-13. PeptideClear is editorial. We do not prescribe, dispense or sell medicines.

Check it yourself: the official sources

PeptideClear is editorial. Nothing here replaces the regulator, and you should not take our word for any of it. These are the official UK destinations where the underlying position is published, free to read and open to anyone.

  • MHRA

    MHRA Products portal

    The Summary of Product Characteristics and Patient Information Leaflet for every medicine licensed in the UK. This is the authoritative document for what a medicine is licensed to do.

  • MHRA

    Drug Safety Update

    The MHRA monthly bulletin of safety advice for prescribers and patients. Where new risks and product information changes are formally announced.

  • MHRA

    Report a fake or illegally supplied medicine

    The MHRA route for reporting a website or seller supplying medicines illegally, and for reporting a product you believe is counterfeit.

  • Advertising Standards Authority

    CAP Code and ASA rulings

    The UK advertising rules, including the ban on advertising prescription-only medicines to the public, and the published rulings that show how they are applied.

  • World Anti-Doping Agency

    WADA Prohibited List

    The annually updated list of substances and methods banned in sport. Many research peptides sit under S0 or S2. UK Anti-Doping enforces it on tested athletes.

  • legislation.gov.uk

    Human Medicines Regulations 2012

    The legislation that defines what counts as a medicine in the UK, and what constitutes illegal supply. A product marketed with medicinal claims is regulated as a medicine regardless of how it is labelled.

Our live data trackers

PeptideClear maintains these as refreshable datasets rather than one-off articles. Each carries its own source, methodology and last-updated date.

Reviewed by Oliver Mackman, editorial director · last reviewed 2026-07-13T12:00:00.000Z
Trust, Legal and Governance

PeptideClear is a trading name of Best Business Loans Ltd, registered in England and Wales (company number 16833937). All services, operations and publications under the PeptideClear brand are delivered by Best Business Loans Ltd.

Legal and Registration

Registered in England and Wales. Company number 16833937. D‑U‑N‑S 234324824. ICO registered, reference ZC151816 (certificate, verify). Registered supplier on the UK Government's Find a Tender Service (FTS). Details publicly available via Companies House and OpenCorporates.

Standards and Governance

Operates under UK data protection and consumer standards. Aligns with UK GDPR, ISO 27001 and ISO 9001 principles. Working towards Cyber Essentials certification.

Domain Continuity

Primary domain peptideclear.co.uk. Business ownership, entity and services remain unchanged. Reviewed quarterly.