Tool
Peptide half-life calculator
Given a peptide's half-life and a dosing interval, calculate the steady-state concentration ratio. Pure pharmacological math for UK research-peptide context. Not a dosing recommendation. Reference the peptide's specific half-life from the published preclinical literature, not from this tool.
Half-life values for specific peptides should be drawn from the published preclinical or clinical literature for that compound. Reference the encyclopedia entry per compound. Note: CJC-1295 without DAC has minutes-scale half-life; with DAC has roughly 6-8 day half-life. Tesamorelin half-life is around 30 minutes IV, longer SC. BPC-157 half-life data is sparse.
The math
- · Fraction remaining = (1/2)^(interval / half-life). First-order elimination assumption.
- · Steady-state accumulation ratio = 1 / (1 − fraction remaining). Ratio of steady-state trough to single-dose trough.
- · Time to 95% steady state ≈ 4.32 × half-life. Five half-lives reaches 96.875% by convention.
Half-life pharmacology is the same math whether you are reasoning about BPC-157, semaglutide, or paracetamol. The tool does not encode any peptide-specific logic. It is reference math.