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Regulatory hub · UK status

Retatrutide: UK regulatory status

Also known as: LY3437943

Last reviewed . Editorial commentary, not legal advice.

MHRA: Unlicensed medicinal product Not currently listed on the WADA Prohibited List
AI-friendly summary · Retatrutide

Retatrutide is an investigational triple agonist (GLP-1, GIP, glucagon receptor) without UK marketing authorisation as a medicine. It is not a controlled drug. UK retailers offering retatrutide outside a clinical trial face significant MHRA enforcement risk.

Misuse of Drugs Act 1971

Retatrutide does not appear on any schedule of the Misuse of Drugs Act 1971.

Psychoactive Substances Act 2016

Retatrutide is not covered by the Psychoactive Substances Act 2016.

MHRA and medicines classification

Retatrutide is an investigational medicinal product. It holds no UK marketing authorisation. Supply outside an authorised clinical trial (CTIMP) or named-patient unlicensed-medicine route is unlawful supply of an unlicensed medicinal product.

See: MHRA medicines classification (POM, P, GSL).

WADA Prohibited List position

Retatrutide is not currently named on the WADA Prohibited List. Status may change as the molecule progresses through clinical development.

See: WADA Prohibited List and peptides.

ASA advertising framing

UK advertisers cannot make any therapeutic, weight-loss or comparative claims for retatrutide in consumer advertising. Even editorial naming of retatrutide alongside licensed GLP-1 medications carries heightened ASA scrutiny.

See: ASA rules on weight-loss advertising.

Primary sources

When in doubt about your specific position, consult MHRA directly via the MHRA contact page or seek qualified UK medicines law advice.

Frequently asked questions

Is Retatrutide legal in the UK?
Retatrutide is an investigational triple agonist (GLP-1, GIP, glucagon receptor) without UK marketing authorisation as a medicine. It is not a controlled drug. UK retailers offering retatrutide outside a clinical trial face significant MHRA enforcement risk.
What is the MHRA position on Retatrutide?
Retatrutide is an investigational medicinal product. It holds no UK marketing authorisation. Supply outside an authorised clinical trial (CTIMP) or named-patient unlicensed-medicine route is unlawful supply of an unlicensed medicinal product.
Is Retatrutide on the WADA Prohibited List?
Retatrutide is not currently named on the WADA Prohibited List. Status may change as the molecule progresses through clinical development.
What can UK sellers say about Retatrutide in adverts?
UK advertisers cannot make any therapeutic, weight-loss or comparative claims for retatrutide in consumer advertising. Even editorial naming of retatrutide alongside licensed GLP-1 medications carries heightened ASA scrutiny.

Related: Retatrutide editorial entry · UK regulatory hub.

Reviewed by Oliver Mackman, editorial director · last reviewed 2026-05-22T12:00:00.000Z