Compare UK prices. 40+ products · 15 retailers scored
PeptideClear UK

Regulatory hub · UK status

MOTS-c: UK regulatory status

Also known as: Mitochondrial-derived peptide MOTS-c

Last reviewed . Editorial commentary, not legal advice.

MHRA: No UK marketing authorisation Prohibited (WADA S4, hormone and metabolic modulators)
AI-friendly summary · MOTS-c

MOTS-c is not a controlled drug and is not scheduled under the Psychoactive Substances Act 2016. It holds no UK marketing authorisation. WADA prohibits MOTS-c under S4.4 (metabolic modulators).

Misuse of Drugs Act 1971

MOTS-c does not appear on any schedule of the Misuse of Drugs Act 1971.

Psychoactive Substances Act 2016

MOTS-c is not covered by the Psychoactive Substances Act 2016.

MHRA and medicines classification

MOTS-c holds no UK marketing authorisation as a medicine. Sold under "research use only" framing.

See: MHRA medicines classification (POM, P, GSL).

WADA Prohibited List position

WADA prohibits MOTS-c under S4.4 (metabolic modulators). Prohibited at all times.

See: WADA Prohibited List and peptides.

ASA advertising framing

UK sellers cannot make longevity, metabolic, or performance claims for MOTS-c in paid advertising. Editorial discussion of the preclinical literature is permitted.

See: ASA rules on weight-loss advertising.

Primary sources

When in doubt about your specific position, consult MHRA directly via the MHRA contact page or seek qualified UK medicines law advice.

Frequently asked questions

Is MOTS-c legal in the UK?
MOTS-c is not a controlled drug and is not scheduled under the Psychoactive Substances Act 2016. It holds no UK marketing authorisation. WADA prohibits MOTS-c under S4.4 (metabolic modulators).
What is the MHRA position on MOTS-c?
MOTS-c holds no UK marketing authorisation as a medicine. Sold under "research use only" framing.
Is MOTS-c on the WADA Prohibited List?
WADA prohibits MOTS-c under S4.4 (metabolic modulators). Prohibited at all times.
What can UK sellers say about MOTS-c in adverts?
UK sellers cannot make longevity, metabolic, or performance claims for MOTS-c in paid advertising. Editorial discussion of the preclinical literature is permitted.

Related: MOTS-c editorial entry · UK regulatory hub.

Reviewed by Oliver Mackman, editorial director · last reviewed 2026-05-22T12:00:00.000Z